09 nov: SAS skruer op for aktiesalget og regner med 25 pct. ekstra i kass..
09 nov: Bavarian sætter gang i ekstra fase 2-forsøg med vaccine
09-11-2017 07:30:13

Bavarian Nordic Announces Initiation of Phase 2 Booster Study of its Universal RSV Vaccine

Relateret indhold
21 sep - 
Aktier/åbning: Danske Bank skraber bunden i positivt el..
19 sep - 
Aktier/åbning: Danske og Borgen falder efter hvidvaskko..
19 sep - 
Aktier/tendens: Danske Bank og Mærsk stjæler billedet
Relateret debat
22 sep - 
Det ved jeg ikke noget om, kun at, der er flertal af kø..
22 sep - 
Det er meget langt ude i fremtiden. Fase 2 er ikke star..
22 sep - 
Men vil du virkelig mene, den har kræfter nok til at be..

  • Study to help determine if MVA-BN RSV will be administered as a seasonal vaccine or if a single shot is effective for multiple seasons

COPENHAGEN, Denmark, November 9, 2017 - Bavarian Nordic A/S (OMX: BAVA, OTC: BVNRY) announced today that dosing has commenced in the Phase 2 extension study of MVA-BN® RSV, a universal vaccine candidate designed to elicit a broad antibody and T-cell response against multiple respiratory syncytial virus (RSV) antigens. This study is designed to help determine whether a single shot administration of vaccine is required annually, or if it remains effective over multiple seasons. The vaccine has previously shown to induce an immune response against RSV for a single season.

The initial Phase 2 study enrolled 421 volunteers to determine dose and response to MVA-BN RSV. This added booster portion of the study will enroll 86 of these subjects to receive a single shot of either low (1x108) or high (5x108) dose of the vaccine. The study will determine what, if any, boosting effect is seen from the additional shot when compared to the balance of subjects in the Phase 2 study, helping to determine whether MVA-BN RSV should be administered annually, or if the durability of the vaccine could extend across multiple seasons.

"The development of an RSV vaccine continues to be a significant healthcare need in our world today. Our plan of development is not only to establish the duration of response from our vaccine, which has already shown activity out to 6 months, but also to implement a human challenge study next year, which will give us an early indication of what level of efficacy we can anticipate with this vaccine," said Paul Chaplin, President & Chief Executive Officer of Bavarian Nordic.

About Bavarian Nordic

Bavarian Nordic is a fully integrated biotechnology company focused on the development of innovative and safe therapies against cancer and infectious diseases. Using our live virus vaccine platform technology, MVA-BN®, we have created a diverse portfolio of proprietary and partnered product candidates intended to improve the health and quality of life for children and adults. We supply our IMVAMUNE® non-replicating smallpox vaccine to the U.S. Strategic National Stockpile and other government stockpiles. The vaccine is approved in the European Union (under the trade name IMVANEX®) and in Canada. Registration studies are currently underway in the U.S. In addition to our long-standing collaboration with the U.S. government on the development of IMVAMUNE® and other medical countermeasures, our infectious disease pipeline comprises a proprietary RSV program as well as vaccine candidates for Ebola, HPV, HBV and HIV, which are developed through a strategic partnership with Janssen. Additionally, in collaboration with the National Cancer Institute, we have developed a portfolio of active cancer immunotherapies, designed to alter the disease course by eliciting a robust and broad anti-cancer immune response while maintaining a favorable risk-benefit profile. Through multiple industry collaborations, we seek to explore the potential synergies of combining our immunotherapies with other immune-modulating agents, e.g. checkpoint inhibitors. For more information visit www.bavarian-nordic.com or follow us on Twitter @bavariannordic.

Forward-looking statements

This announcement includes forward-looking statements that involve risks, uncertainties and other factors, many of which are outside of our control, that could cause actual results to differ materially from the results discussed in the forward-looking statements. Forward-looking statements include statements concerning our plans, objectives, goals, future events, performance and/or other information that is not historical information. All such forward-looking statements are expressly qualified by these cautionary statements and any other cautionary statements which may accompany the forward-looking statements. We undertake no obligation to publicly update or revise forward-looking statements to reflect subsequent events or circumstances after the date made, except as required by law.

Contacts

Rolf Sass Sørensen

Vice President Investor Relations (EU)

Tel: +45 61 77 47 43

Seth Lewis

Vice President Investor Relations (US)

Tel: +1 978 341 5271

Company Announcement no. 30 / 2017

2017-30-en


This announcement is distributed by Nasdaq Corporate Solutions on behalf of Nasdaq Corporate Solutions clients.

The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.

Source: Bavarian Nordic A/S via Globenewswire

Vedhæftet fil: 824171.pdf

Opret kommentar

Relateret debat

  • 1 uge
  • 1 måned
  • 1 År
16 sep
BAVA
Bava var sat op til en næsten perfekt IHS, der ville sende den op i ca. 225.   Men så kommer der lig..
14
17 sep
BAVA
dette er en delvis gentagelse af mit indlæg fra weekenden Min tilgang til den er at jeg ikke forstå..
12
19 sep
BAVA
Hej alle, Nu er videoen oppe fra Investordagen i går. Den kan ses her: https://getvisualtv.net..
9
16 sep
BAVA
Jeg tror ikke på shorterne kan købe sig til en negativ rapport fra Kemp. De har bare været negativ h..
8
21 sep
BAVA
Det er ikke så svært at finde grunden. Rigtig ofte vinder hedgefondene på deres shorts. Nogle gange ..
7
18 sep
BAVA
Hvad med om moderator bare sletter hele tråden! Den er jo kun startet for at skabe splid!
6
21 sep
BAVA
Du har da ret i, at når Wace fonden for nyligt har øget i Bavarian, er det ikke sket til 250. Men je..
4
21 sep
BAVA
Jeg havde en frygt for, at BAVA kunne møde modstand her ved 175, og det ser meget aktuelt ud. Ved si..
4
17 sep
BAVA
AXSchmidt, du mangler i højeste grad selvreflektion. Evnen til at debattere er tåkrummende lav. D..
4
17 sep
BAVA
Så er du her igen... 2,1 mia i kassen plus et bevis næste år som kan sælges til mellem 100-300 mio U..
4

Danske: Moody's ser risiko for sænkning af kreditvurderingen - NY

21-09-2018 15:14:23
Moody's Investors Service er gået i gang med at kigge kreditvurderingen af Danske Bank efter i sømmene og forudser, at der er risiko for en nedjustering. Det oplyser ratinginstituttet fredag, hvor udsigten for Danske Banks kreditvurdering er sænket til "negativ" fra "stabil".Ændringen kommer, efter at banken har offentliggjort rapporten om hvidvask i sin estiske filial tidligere på ugen, skriver M..

Mærsk/Sydbank: Fundamentaler peger ikke mod gode fragtrater

21-09-2018 11:08:55
Efter en periode med overvejende positiv udvikling i fragtraterne er rateindekset Shanghai Containerized Fright Index, SCFI, nu faldet tre uger i træk. Den negative udvikling stopper dog ikke nødvendigvis her, vurderer senioranalytiker Morten Imsgard fra Sydbank, der dækker A.P. Møller-Mærsk. - Nu har vi set tre uger i træk, så det er lidt en trend, men ellers er der stor udsving i de her ugentlig..

Aktier/tendens: Danske Bank trækker overskrifter i ventet grønt marked

21-09-2018 08:04:56
Danske Bank kan fredag komme under investorernes kritiske lup, efter at flere danske aviser endnu engang har banken og undersøgelsen af dens rolle i hvidvasksagen som forsidestof.Børsen kan berette, at selskabet Deminor, der er ekspert i gruppesøgsmål, vil forsøge at samle opbakning blandt aktionærerne til en ny granskning af hvidvasksagen. I Jyllands-Posten Erhverv mener flere eksperter, at det e..

Mest læste nyheder

  • 24 timer
  • 48 timer
  • 1 uge

Relaterede aktiekurser

Bavarian Nordic A/S 173,70 -0,1% Fald i aktiekurs
Bavarian Nordic Ord Shs 173,70 -0,1% Fald i aktiekurs

Køb- og salgsanbefalinger

  • Trend
  • Pengemaskinen

Copyright Berlingske Media 2018  Handelsbetingelser  |  Cookiedeklaration  |  Cookie- og Privatlivspolitik  |  Ophavsret og vilkår
Aktieinformation leveres af Morningstar.
Data er forsinket 15-20 minutter iht. de enkelte børsers regler om videredistribution.
 
23. september 2018 00:34:06
(UTC+01:00) Brussels, Copenhagen, Madrid, Paris
Version: LiveBranchBuild_20180919.1 - EUROWEB1 - 2018-09-23 00:34:06 - 2018-09-23 00:34:06 - 1 - Website: OKAY